Based on the configuration of plant-wide steam network of chemical enterprises, a program control response strategy is proposed for the fluctuation of steam network. Program control is used to replace human decision-making to avoid the secondary accident caused by untimely decision-making or insufficient emergency response capacity of personnel, reduce economic loss and ensure the safety of the plant. When the steam turbine of large compressor unit trips, in order to avoid the fluctuation of steam network, a program control scheme is proposed according to the characteristic parameters of the control valve of temperature and pressure reducer to stabilize the pressure of steam network in time and reduce the economic loss caused by process fluctuations.