In ethylene plants, volatile hydrocarbons and dissolved gases are stripped from process water in process water stripper and sent to quench water tower. The stable operation of process water stripper can effectively ensure the stable operation of ethane feed saturator and steam standby generator. During practical operation, due to factors such as instrument failures and process fluctuations, there is a loss of pressure in the process water stripper, which seriously affects the stable operation of the process. This article proposes some effective measures against the loss of pressure in process water stripper, analyzes the reasons for the loss of pressure, and proposes some process improvement measures to ensure the stable operation of process water stripper.