This paper mainly studies the anti-corrosion design of chemical concentrated sulfuric acid pipelines in the petrochemical industry and the corrosion performance of concentrated sulfuric acid on carbon steel pipeline materials, analyzes the key corrosion parts of the concentrated sulfuric acid pipelines based on the test and the collection of relevant data, and compares the corrosion of two concentrated sulfuric acid pipelines. The reasons for the difference in corrosion rates of carbon steel pipelines in different parts under different conditions are analyzed, and the key rules for anti-corrosion are found out to reduce the leakage caused by the corrosion of concentrated sulfuric acid pipelines.